★★★★★
"I was introduced to De Simone's VSL#3 two years ago after a bad digestion issue. A consultant suggested it. Moved to Vivomixx as couldn't get in UK. Saw it is now available under De Simone's own label. Very pleased."
Is Visbiome Available in the UK? Yes, meet CDS22-formula.
🔬 Visbiome searchers — read this first
Is Visbiome Available
in the UK? Yes,
meet CDS22-formula.
Visbiome and CDS22-formula share the same scientific origin. Same De Simone Formulation. Same 8 strains. CDS22-formula is available in the UK now.
Shop CDS22-formula — available in the UK →
From £14.99 per pack · Free cold-chain delivery over £65 · Next-day UK
Cold-chain DPD — live cultures protected door to door
Next-day UK delivery available
Official UK & Ireland distributor
4.9/5 · 161 verified Trustpilot reviews
UK availability
Visbiome in the UK — what you need to know.
Visbiome is not sold in the UK or Ireland.
It is a US-only product. If you are searching for Visbiome in the UK, CDS22-formula is the closest available alternative — same formulation origin, same 8 strains, 450 billion CFU per sachet.
Fact 01
Visbiome and CDS22-formula share the same scientific origin: the De Simone Formulation developed by Professor Claudio De Simone. The same scientist. The same 8 bacterial strains. The same 450 billion CFU formulation principle.
Fact 02
The De Simone Formulation was originally sold as VSL#3 until 2016. In Europe it became Vivomixx. In 2024-25 it became CDS22-formula. Visbiome was developed for the US market by Professor De Simone using the same formulation.
Fact 03
CDS22-formula is the only product in the UK and Ireland carrying the De Simone Formulation. In stock now. Cold-chain DPD delivery. Next-day available nationwide.
If you were recommended the De Simone Formulation and are searching for Visbiome in the UK, CDS22-formula is what you are looking for. Same formulation origin. Available now in the UK.
Side by side
Visbiome vs CDS22-formula
| Feature | Visbiome | CDS22-formula |
|---|---|---|
| Formulation | De Simone Formulation | De Simone Formulation ✓ |
| Scientist | Prof. Claudio De Simone | Prof. Claudio De Simone ✓ |
| Strains | 8 strains | 8 strains ✓ |
| CFU per sachet | 450 billion | 450 billion ✓ |
| Available in UK | No ✗ | Yes — in stock ✓ |
| Cold-chain delivery | Not UK | DPD next-day UK ✓ |
| Market | US only | UK & Ireland ✓ |
Brand note Visbiome® is a registered trademark of ExeGi Pharma LLC, US. No affiliation to Visbiome or ExeGi Pharma exists. CDS22-formula is an independent product distributed in the UK & Ireland by Probiotic.co.uk. This comparison is provided for factual product identification purposes only.
The De Simone Formulation.
Available in the UK now.
Shop CDS22-formula →
From £14.99 per pack · Free cold-chain delivery over £65 · Next-day UK
450B CFU per sachet — original DSF
8 Original De Simone strains
❄️ Cold-chain DPD delivery
🇬🇧 Official UK distributor
❄️ Free cold-chain delivery on orders over £65
3 packs: £2.65/pack shipping · 4+ packs: free shipping
3 packs: £2.65/pack shipping · 4+ packs: free shipping
Buy 2 — save £2.00
24 sachets total
£39.00
£37.00
Most popular
Buy 3 — save £8.00
36 sachets · £16.83/pack · free delivery
£58.50
£50.50
Buy 4 — save £15.50
48 sachets · free delivery
£78.00
£62.50
Buy 5 — save £23.00
60 sachets · free delivery
£97.50
£74.50
Buy 6 — save £27.01
72 sachets · £14.99/pack · free delivery
£117.00
£89.99
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Verified Trustpilot reviews
What customers say after finding the original formula
4.9 / 5 · Excellent
★★★★★
161 verified reviews
★★★★★
"Great to see Irish market offering the best range of supplements and my trusted Probiotics CDS22 aka VSL#3. I was disappointed that I couldn't buy VSL#3 from my regular UK supplier."
★★★★★
"Delivery super quick and well packaged. This is my 3rd time of ordering and it's definitely helped with my j pouch function. I'm so grateful I can still get this probiotic formula after Vivomixx stopped selling."
★★★★★
"I used Vivomixx for quite some time then moved to CDS22-formula. This is an excellent probiotic. I have gut issues — by using CDS22 it helps me a lot. I would certainly recommend this product."
Cold-chain delivery
Live cultures. Protected all the way.
Packed cold in LancashireTemperature-controlled from the moment your order is picked at our UK facility — Matrix Park, Chorley, PR7 7NB.
Shipped refrigerated via DPDCold-chain throughout transit. Next-day delivery available nationwide. Free over £65.
Refrigerate on arrivalTransfer to your fridge immediately. Live cultures must be kept cold to maintain viability.
Full cold-chain details: probiotic.co.uk/pages/cds22-delivery-information
Shop CDS22-formula → Clinical heritage
The most clinically studied probiotic formulation in the UK.
80+Clinical studies on this exact formulation
200+Scientific publications
450BCFU per sachet
4.9★161 Trustpilot reviews
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Referenced in ECCO guidelines for Inflammatory Bowel Disease management (ECCO News, 2023)
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Referenced in American College of Gastroenterology guidance for pouchitis (Olleik et al., Gastroenterology, Vol. 164, No. 6, 2023)
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NHS Patient Access Programme available via Probiotic.co.uk
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Exclusive UK & Ireland distributor — Probiotic.co.uk, Chorley, Lancashire
Related pages
Learn more about the De Simone Formulation
Common questions
Visbiome UK — frequently asked
Is Visbiome available in the UK?
No. Visbiome is not sold in the UK or Ireland. It is a US-only product. The closest available UK equivalent is CDS22-formula — same De Simone Formulation, same 8 strains, 450 billion CFU. Available now with cold-chain next-day delivery from Probiotic.co.uk.
What is the connection between Visbiome and CDS22-formula?
Both Visbiome and CDS22-formula are based on the De Simone Formulation — an 8-strain probiotic formulation developed by Professor Claudio De Simone. Visbiome is the US-market product. CDS22-formula is the current UK and Ireland product. They share the same scientific heritage, the same formulation principle, and the same 8 bacterial strains at 450 billion CFU.
What is the De Simone Formulation?
The De Simone Formulation (DSF) is a specific 8-strain probiotic formulation developed by Professor Claudio De Simone. It has been the subject of over 80 peer-reviewed clinical studies and is referenced in ECCO guidelines for Inflammatory Bowel Disease management and American College of Gastroenterology guidance for pouchitis. CDS22-formula contains this exact formulation.
Where can I buy Visbiome in the UK?
Visbiome is not sold in the UK. It is a US-only product. The closest UK equivalent is CDS22-formula, which contains the same De Simone Formulation. CDS22-formula is available exclusively through Probiotic.co.uk with cold-chain DPD next-day delivery across the UK.
Is Visbiome the same as VSL#3?
Visbiome and VSL#3 share a common scientific origin in the De Simone Formulation. The original formulation was sold as VSL#3 until 2016, became Vivomixx in Europe, and became CDS22-formula in 2024-25. Visbiome was developed separately for the US market by Professor Claudio De Simone using the same formulation principles. In the UK, CDS22-formula is the product that carries this formulation.
How is CDS22-formula delivered in the UK?
CDS22-formula contains live bacteria and must be refrigerated. We ship cold-chain via DPD from our temperature-controlled facility in Lancashire. Next-day delivery available nationwide. Free cold-chain delivery on orders over £65. Refrigerate immediately on arrival.
My doctor recommended the De Simone Formulation — is this the right product?
CDS22-formula is the current UK brand for the De Simone Formulation, which is referenced in ECCO and American College of Gastroenterology clinical guidelines. Always confirm any product change with your clinical team before switching.
Where can I see the full ingredients and product details?
Full ingredients, allergens, usage guidance, and product information are on the product page at probiotic.co.uk. Please review all product details before purchasing, particularly if you are under clinical supervision or have known allergies.
The De Simone Formulation.
Available in the UK now.
Visbiome is not sold in the UK. CDS22-formula is. Same scientific origin. Same 8 strains. 450 billion CFU. Cold-chain DPD. Next-day UK delivery. From £14.99 per pack.
Shop CDS22-formula →4.9★ Trustpilot · 161 verified reviews · Official UK distributor · Secure checkout
Free cold-chain delivery over £65 · Next-day DPD
Free cold-chain delivery over £65 · Next-day DPD