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CDS22-formula (Original De Simone Formulation)

1. Original De Simone Formulation

The same clinically validated formulation used in all published VSL#3 research before 2016.

2. Backed by 80+ Peer-Reviewed Clinical Trials

Every trial behind VSL#3’s reputation was conducted using this original formulation.

3. Authored by the Inventor Himself

Created and certified by Prof. Claudio De Simone — the originator and developer of the formula sold for years as VSL#3.

4. Proven Clinical Continuity

No reformulation. No changes. Same strain mix, same ratios, same evidence base.

5. Manufactured Under Original Standards

European production with full cold-chain handling as referenced in the clinical file.

6. Exclusive UK & Ireland Availability

The original formulation is now sold exclusively as CDS22-formula in the UK and Ireland.

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VSL#3 (Post-2016 Reformulated Version)

1. No Longer the Original Formulation

Court-confirmed that post-2016 VSL#3 is not the original De Simone Formulation.

2. Class-Action Lawsuit in the U.S.

A federal judge certified a class action alleging the formula change misled consumers.

3. Previously Found Liable for Misrepresentation

A U.S. jury awarded $18M in damages for falsely implying continuity of the original formula.

4. Reformulated Without the Inventor’s Involvement

Prof. De Simone had no role in the new VSL#3 formula.

5. Switch Not Communicated Clearly to Consumers

The court found customers believed they were still buying the original formulation when they were not.