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CDS22-Formula | Original De Simone Formulation UK Probiotic (450 Billion CFU) | Larger 12 Sachet Pack
£19.95
Regular price
£23.95
CDS22-Formula 112 Billion CFU Probiotic | 20 Capsules
£17.90
CDS22-Formula Infant Drops | 8 Strains | 2 x 5ml
£13.55
Regular price
£14.95
CDS22-Formula – The Original De Simone UK Probiotic (450 Billion CFU Per Sachet)
CDS22-formula: an 8-strain live bacteria supplement
CDS22-formula is an 8-strain live bacteria food supplement, available in 450 billion CFU sachets, 112 billion CFU capsules and infant drops. The formulation was developed by Professor Claudio De Simone. It is manufactured by EOS2021 S.r.l. and supplied in the United Kingdom by Probiotic.co.uk, cold-chain protected from receipt to delivery.
Every product in this range carries the same eight strains, identified on the current UK label by their NCIMB deposit codes. Deposit codes are neutral public identifiers, which makes them the most reliable way to confirm what a live bacteria supplement actually contains.
CDS22-formula is a food supplement, not a medicine. It is not licensed by the MHRA and it is not intended to diagnose, treat, cure or prevent any disease or health condition. No authorised UK or EU health claim is made for CDS22-formula or for any of its bacterial strains on this page.
Probiotic.co.uk is an independent company. We are the authorised United Kingdom and Ireland distributor of CDS22-formula, which is manufactured by EOS2021 S.r.l. We are not affiliated with, endorsed by, sponsored by or connected to any other probiotic manufacturer, brand owner or trademark holder.
Product composition, strain designations and specifications can change. Always check the current pack label before use.
The range at a glance
- Formulation: 8 strains, identified by NCIMB deposit code (NCIMB 30435 to NCIMB 30442)
- Formats: 450 billion CFU sachets · 112 billion CFU capsules · infant drops
- Manufacturer: EOS2021 S.r.l.
- UK distributor: Probiotic.co.uk, authorised United Kingdom and Ireland distributor
- Storage: refrigerated +2°C to +8°C · shelf-stable up to 7 days at 25°C per the manufacturer's storage leaflet
- Delivery: cold-chain protected, dispatched from a temperature-controlled UK facility
- Regulatory status: food supplement under UK food law · 20% VAT applies
Choose your format
Every product in this range contains the same eight NCIMB-identified strains. They differ by format and by live count per serving.
450B Sachets
The highest live count per serving in the range. A powder mixed into a cool drink or yogurt. Available in larger multi-packs and on subscription.
View the sachets →112B Capsules
A vegetable capsule for a simple daily routine and for travel. A lower live count per serving than the sachets.
View the capsules →Infant Drops
Presented in a drop format for babies and young children. Check the pack for the age guidance and dosage.
View the drops →All packs, multi-buy bundles and subscription options are listed in the product grid on this page. Speak to your GP, pharmacist, midwife or health visitor before giving any food supplement to a baby or young child.
The eight strains and their NCIMB deposit codes
Across every format, the formulation is defined by the same eight strains. The current UK label identifies each one by its NCIMB deposit code, so it can be checked against a public register rather than taken on trust. Total live count per serving varies by product: 450 billion CFU per sachet, 112 billion CFU per capsule.
| Strain | NCIMB deposit code |
|---|---|
| Streptococcus thermophilus | NCIMB 30438 |
| Bifidobacterium breve | NCIMB 30441 |
| Bifidobacterium animalis subsp. lactis | NCIMB 30435 |
| Bifidobacterium animalis subsp. lactis | NCIMB 30436 |
| Lactobacillus acidophilus | NCIMB 30442 |
| Lactobacillus plantarum | NCIMB 30437 |
| Lactobacillus paracasei | NCIMB 30439 |
| Lactobacillus helveticus | NCIMB 30440 |
Strain designations are taken from the current UK pack label supplied by the manufacturer, EOS2021 S.r.l. Under updated bacterial taxonomy some of these organisms have been reclassified and appear under earlier names in older literature. Always check the current pack label, as specifications can change.
Cold-chain handled, end to end
Every product in this range is a live-culture supplement, so handling matters. We receive it refrigerated from the manufacturer, hold it in dedicated refrigeration at our UK facility, and dispatch it cold-chain protected. Per the manufacturer's storage leaflet it stays shelf-stable at room temperature up to 25°C for up to seven days, which covers normal UK transit. Refrigerate on arrival. See our cold-chain delivery information.
"As the authorised UK and Ireland distributor, we handle every order under strict cold-chain protocols, from the manufacturer through to your door. That is the part we control, and it is the part that protects the live count you are paying for."
— Darren Grant, Managing Director, Probiotic.co.uk
Probiotic.co.uk is appointed by the manufacturer, EOS2021 S.r.l., as authorised distributor for the United Kingdom and Ireland. Selecting the United Kingdom or Ireland on the manufacturer's website, cds22.com, directs customers here.
Guides and resources
Background reading is kept separate from this product page. These guides are educational and do not make any claim for the products sold here.
Frequently asked questions
What is CDS22-formula?
CDS22-formula is an 8-strain live bacteria food supplement manufactured by EOS2021 S.r.l. The formulation was developed by Professor Claudio De Simone. Its eight strains are identified on the current UK label by their NCIMB deposit codes, NCIMB 30435 to NCIMB 30442. The range sold by Probiotic.co.uk includes 450 billion CFU sachets, 112 billion CFU capsules and infant drops. CDS22-formula is a food supplement, not a medicine.
Which strains are in CDS22-formula?
Eight strains, identified by their NCIMB deposit codes: Streptococcus thermophilus NCIMB 30438, Bifidobacterium breve NCIMB 30441, Bifidobacterium animalis subsp. lactis NCIMB 30435 and NCIMB 30436, Lactobacillus acidophilus NCIMB 30442, Lactobacillus plantarum NCIMB 30437, Lactobacillus paracasei NCIMB 30439 and Lactobacillus helveticus NCIMB 30440. Deposit codes identify specific strains and are the most reliable way to confirm what a live bacteria supplement contains. The total live count per serving depends on the product format.
Which format should I choose: sachets, capsules or drops?
All three formats contain the same eight NCIMB-identified strains and differ by format and live count per serving. The 450 billion CFU sachets are a powder mixed into a cool drink or yogurt and carry the highest count per serving. The 112 billion CFU vegetable capsules suit a simple daily routine and travel. The infant drops are presented in a drop format for babies and young children. The choice is format preference and the live count you want per serving.
What is the difference between the 450 billion and 112 billion products?
Both contain the same eight NCIMB-identified strains. The difference is format and live count per serving. The sachets provide 450 billion CFU per sachet as a powder. The capsules provide 112 billion CFU per vegetable capsule.
Who is the authorised UK distributor of CDS22-formula?
Probiotic.co.uk is the authorised United Kingdom and Ireland distributor of CDS22-formula, appointed by the manufacturer EOS2021 S.r.l. On the manufacturer's website, cds22.com, selecting the United Kingdom or Ireland directs customers to Probiotic.co.uk. Probiotic.co.uk is an independent company and is not connected to any other probiotic manufacturer or brand owner.
Why does CDS22-formula need cold-chain delivery?
CDS22-formula contains live bacteria. The manufacturer specifies refrigerated storage at +2°C to +8°C to maintain the stated live count through the shelf life. According to the manufacturer's storage leaflet the product remains shelf-stable at room temperature up to 25°C for up to seven days, which covers normal UK transit. Probiotic.co.uk dispatches every order cold-chain protected from a temperature-controlled UK facility.
How should I store CDS22-formula at home?
Refrigerate at +2°C to +8°C on arrival and keep it refrigerated. Do not freeze. Keep the pack closed and away from direct heat and sunlight. Sachets should be mixed into a cool drink or food rather than a hot one, because heat reduces the live count. Check the best-before date on the pack and keep out of the reach of young children.
Is CDS22-formula a medicine?
No. CDS22-formula is sold in the United Kingdom as a food supplement under UK food law. It is not a medicine, it is not licensed by the MHRA, and it is not intended to diagnose, treat, cure or prevent any disease or health condition. No prescription is required and no authorised health claim is made for it.
CDS22-formula is manufactured by EOS2021 S.r.l. Probiotic.co.uk is an independent company, operated by TenX Tech Ltd, and is the authorised distributor of CDS22-formula for the United Kingdom and Ireland. Probiotic.co.uk is not affiliated with, endorsed by, sponsored by, connected to or distributed by any other probiotic manufacturer, brand owner or trademark holder. Any third-party trademarks referred to elsewhere on this website remain the property of their respective owners.