CDS22-Formula | Original De Simone Formulation UK Probiotic (450 Billion CFU) | Larger 12 Sachet Pack
CDS22-Formula | Original De Simone Formulation UK Probiotic (450 Billion CFU) | Larger 12 Sachet Pack
CDS22-formula is an 8-strain live bacteria food supplement, supplied as 12 sachets with 450 billion live cultures (CFU) per sachet. The formulation was developed by Professor Claudio De Simone and is manufactured by EOS2021 S.r.l. in Italy.
Each of the eight strains is identified on the pack by its NCIMB deposit code, so the contents can be checked against a public register rather than taken on trust. Refrigerated product, cold-chain dispatched across the UK. £19.95 per pack.
CDS22-formula is a food supplement, not a medicine. It is not licensed by the MHRA and it is not intended to diagnose, treat, cure or prevent any disease or health condition. No authorised UK or EU health claim is made for CDS22-formula or for any of its bacterial strains on this page.
Probiotic.co.uk is an independent company. We are the authorised United Kingdom and Ireland distributor of CDS22-formula, which is manufactured by EOS2021 S.r.l. We are not affiliated with, endorsed by, sponsored by or connected to any other probiotic manufacturer, brand owner or trademark holder.
Product composition, strain designations and specifications can change. Always check the current pack label before use.
At a glance
- Formulation: 8 strains, each identified by NCIMB deposit code (NCIMB 30435 to NCIMB 30442)
- Live bacteria: 450 billion CFU per sachet
- Format: 12 sachets (4.4g each) · powder to mix into a cool drink or yogurt
- Manufacturer: EOS2021 S.r.l., Italy
- Suitability: gluten-free · from age 3, at the reduced serving stated below
- Storage: refrigerate +2°C to +8°C · shelf-stable to 25°C for up to 7 days per the manufacturer's leaflet · 18-month shelf life from manufacture when refrigerated
- Price and dispatch: £19.95 inc. 20% VAT · cold-chain shipped across the UK
The 8 strains in CDS22-formula, per sachet
Each sachet delivers 450 billion live cultures across eight strains. Each strain is identified by its NCIMB deposit code, which is a neutral public identifier and the most reliable way to confirm what a live bacteria supplement contains.
| Strain | NCIMB deposit code | Per sachet |
|---|---|---|
| Streptococcus thermophilus | NCIMB 30438 | 226 billion |
| Lactobacillus acidophilus | NCIMB 30442 | 38 billion |
| Lactobacillus plantarum | NCIMB 30437 | 38 billion |
| Lactobacillus paracasei | NCIMB 30439 | 38 billion |
| Lactobacillus helveticus | NCIMB 30440 | 38 billion |
| Bifidobacterium breve | NCIMB 30441 | 24 billion |
| Bifidobacterium animalis subsp. lactis | NCIMB 30435 | 24 billion |
| Bifidobacterium animalis subsp. lactis | NCIMB 30436 | 24 billion |
| Total live cultures per sachet | 450 billion | |
Strain designations are taken from the current UK pack label supplied by the manufacturer, EOS2021 S.r.l. Under updated bacterial taxonomy some of these organisms have been reclassified and appear under earlier names in older literature. Always check the current pack label, as specifications can change.
Why buy from Probiotic.co.uk
- Cold-chain handled end to end: received refrigerated from the manufacturer, held in dedicated refrigeration at our UK facility, then dispatched cold, so the live count on the label is the count you receive
- Appointed by the manufacturer, EOS2021 S.r.l., as authorised distributor for the United Kingdom and Ireland
- Eight strains, each identified by NCIMB deposit code so you can verify what you are buying
- UK dispatch, so no import duty or customs handling charges
- Tracked delivery across the UK including Northern Ireland
How we deliver a refrigerated probiotic, safely
A common question: will a refrigerated product survive shipping? Per the manufacturer's storage leaflet, CDS22-formula stays shelf-stable at room temperature up to 25°C for up to 7 days, so a normal 24 to 48 hour delivery does not affect the live cultures, even if an ice pack has melted on arrival. We still ice-pack and foil-line every order anyway:
- Easi-Chill coolant packs and insulated foil liners, up to 73 hours of chilled protection in transit
- Dispatched Monday to Thursday only, so orders do not sit in a depot over the weekend
- Royal Mail Tracked 24 or DPD Premium Tracked
- Refrigerate on arrival to maintain the live count to the best-before date
How to use
- Adults and children aged 7 and over: 1 to 2 sachets per day
- Children aged 3 to 6: up to half a sachet per day
- Open and mix into a cool, non-fizzy drink, yogurt or fruit juice, and consume immediately
- Do not add to hot liquids, as heat reduces the live count
- Do not exceed the recommended daily dose
Speak to your GP or pharmacist before giving any food supplement to a child.
Storage
- Store in the refrigerator (+2°C to +8°C) to maintain the live cultures
- Per the manufacturer's storage leaflet, may be kept at room temperature up to 25°C for up to one week
- Avoid temperatures above 25°C. Do not freeze
- 18-month shelf life from manufacture when kept refrigerated
Product details
Food supplement with 450 billion live cultures per sachet. Format: 12 sachets of 4.4g (52.8g total). Manufactured by EOS2021 S.r.l., Italy. Price £19.95 inc. 20% VAT.
Ingredients
Maltose, mixture of lactic ferments (Streptococcus thermophilus NCIMB 30438, Bifidobacterium breve NCIMB 30441, Bifidobacterium animalis subsp. lactis NCIMB 30435, Bifidobacterium animalis subsp. lactis NCIMB 30436, Lactobacillus acidophilus NCIMB 30442, Lactobacillus plantarum NCIMB 30437, Lactobacillus paracasei NCIMB 30439, Lactobacillus helveticus NCIMB 30440). Gluten-free.
The live cell count refers to the product correctly stored in intact packaging at refrigerated temperature (+2°C to +8°C) until the best-before date. Always check the current pack label before use.
Nutritional declaration
| Per 100g | Per sachet (4.4g) | |
|---|---|---|
| Energy | 1554 kJ / 366 kcal | 68.37 kJ / 16.10 kcal |
| Fat | 0.5 g | 0.02 g |
| of which saturates | 0.1 g | 0.00 g |
| Carbohydrate | 80 g | 3.52 g |
| of which sugars | 63 g | 2.77 g |
| Protein | 10 g | 0.44 g |
| Salt | 0.28 g | 0.01 g |
Supply, bundles and subscription
A 12-sachet pack is about 1 to 2 weeks' supply at 1 to 2 sachets a day. For continuous use, the multi-pack bundle and the monthly subscription give a lower price per pack. CDS22-formula keeps for 18 months refrigerated, so stocking up will not go to waste.
Other formats and the full range
- CDS22-formula 112 billion capsules (20-pack) — same eight NCIMB strains, capsule format, lower count per serving
- CDS22-formula Infant Drops — for babies and young children
- All CDS22-formula products — full range
Frequently asked questions
What is CDS22-formula?
CDS22-formula is an 8-strain live bacteria food supplement manufactured by EOS2021 S.r.l. in Italy. The formulation was developed by Professor Claudio De Simone. This product supplies 450 billion live cultures (CFU) per sachet, in packs of 12 sachets of 4.4g. Each strain is identified on the pack by its NCIMB deposit code. CDS22-formula is a food supplement, not a medicine.
How many strains and how much CFU does CDS22-formula contain?
Each sachet contains 8 strains delivering 450 billion live cultures (CFU): Streptococcus thermophilus NCIMB 30438 (226 billion), Lactobacillus acidophilus NCIMB 30442 (38 billion), Lactobacillus plantarum NCIMB 30437 (38 billion), Lactobacillus paracasei NCIMB 30439 (38 billion), Lactobacillus helveticus NCIMB 30440 (38 billion), Bifidobacterium breve NCIMB 30441 (24 billion), and Bifidobacterium animalis subsp. lactis NCIMB 30435 and NCIMB 30436 (24 billion each).
How do I check I am getting the right product?
Check the eight NCIMB deposit codes on the pack: NCIMB 30435, 30436, 30437, 30438, 30439, 30440, 30441 and 30442. Deposit codes identify specific strains against a public register, which makes them a more reliable check than a product name or a count on the front of a box. Also check the stated live count per serving and the best-before date, and buy from a seller who ships live-culture products cold-chain.
Who is the authorised UK distributor of CDS22-formula?
Probiotic.co.uk is the authorised United Kingdom and Ireland distributor of CDS22-formula, appointed by the manufacturer EOS2021 S.r.l. On the manufacturer's website, cds22.com, selecting the United Kingdom or Ireland directs customers to Probiotic.co.uk. Probiotic.co.uk is an independent company and is not connected to any other probiotic manufacturer or brand owner.
What is the difference between the 450 billion sachets and the 112 billion capsules?
Both contain the same eight NCIMB-identified strains. The difference is format and live count per serving. This product is 450 billion CFU per sachet, supplied as a powder to mix into a cool drink or yogurt. The capsule product is 112 billion CFU per vegetable capsule. The choice is format preference and the live count you want per serving.
Does CDS22-formula need to be refrigerated?
Yes. CDS22-formula is a refrigerated product and should be stored at +2°C to +8°C to maintain the live cultures, with an 18-month shelf life from manufacture when kept refrigerated. According to the manufacturer's storage leaflet it can be kept at room temperature up to 25°C for up to one week. Probiotic.co.uk dispatches it cold-chain across the UK.
Will CDS22-formula survive delivery if the ice pack melts?
Yes. CDS22-formula stays stable at room temperature up to 25°C for up to 7 days per the manufacturer's storage leaflet, so a normal 24 to 48 hour delivery does not affect the live cultures even if the ice pack has melted on arrival. We still ice-pack and foil-line every order for up to 73 hours of chilled protection, and dispatch Monday to Thursday. Refrigerate the product on arrival.
How do I take CDS22-formula?
Adults and children aged 7 and over take 1 to 2 sachets per day. Children aged 3 to 6 take up to half a sachet per day. Mix the contents into a cool, non-fizzy drink, yogurt or fruit juice and consume immediately. Do not add to hot liquids, as heat reduces the live count. Do not exceed the recommended daily dose. Speak to your GP or pharmacist before giving any food supplement to a child.
What is in each sachet apart from the bacteria?
Maltose, plus the mixture of eight lactic ferments listed on the pack. Each sachet weighs 4.4g and provides 16.10 kcal, 3.52g carbohydrate of which 2.77g sugars, 0.44g protein, 0.02g fat and 0.01g salt. The product is gluten-free. Always check the current pack label before use, as formulations can change.
Is CDS22-formula a medicine, and is it legal in the UK?
CDS22-formula is sold legally in the United Kingdom as a food supplement under UK food law. It is not a medicine, it is not licensed by the MHRA, and it is not intended to diagnose, treat, cure or prevent any disease or health condition. No prescription is required and no authorised health claim is made for it.
Download the Patient Information Sheet (PDF) · CDS22-formula FAQs · Delivery and storage information
Product details: CDS22-formula · 12 sachets (4.4g) · 450 billion CFU per sachet · 8 strains identified by NCIMB deposit code · manufactured by EOS2021 S.r.l., Italy · gluten-free · authorised UK and Ireland distributor · £19.95 inc. 20% VAT.
CDS22-formula is manufactured by EOS2021 S.r.l. Probiotic.co.uk is an independent company, operated by TenX Tech Ltd, and is the authorised distributor of CDS22-formula for the United Kingdom and Ireland. Probiotic.co.uk is not affiliated with, endorsed by, sponsored by, connected to or distributed by any other probiotic manufacturer, brand owner or trademark holder. Any third-party trademarks referred to elsewhere on this website remain the property of their respective owners.